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Home - Products - Metabolic Enzyme/Protease - P450 - Harman hydrochloride

Harman hydrochloride

CAS No. 21655-84-5

Harman hydrochloride( Harmane hydrochloride(486-84-0 Free base) )

Catalog No. M27979 CAS No. 21655-84-5

Harman hydrochloride can directly induce CYP1A1 gene expression in an AhR-dependent manner and may represent a novel mechanism by which harman promotes mutagenicity, co-mutagenicity and carcinogenicity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 54 In Stock
10MG 77 In Stock
25MG 138 In Stock
50MG 210 In Stock
100MG 314 In Stock
200MG 471 In Stock
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Biological Information

  • Product Name
    Harman hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Harman hydrochloride can directly induce CYP1A1 gene expression in an AhR-dependent manner and may represent a novel mechanism by which harman promotes mutagenicity, co-mutagenicity and carcinogenicity.
  • Description
    Harman hydrochloride can directly induce CYP1A1 gene expression in an AhR-dependent manner and may represent a novel mechanism by which harman promotes mutagenicity, co-mutagenicity and carcinogenicity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Harmane hydrochloride(486-84-0 Free base)
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    Autophagy
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    21655-84-5
  • Formula Weight
    218.68
  • Molecular Formula
    C12H11ClN2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1nccc2c1[nH]c1c2cccc1.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Páchniková G, et al. Substituted 2-hydroxy-N-(arylalkyl)benzamide sensitizes cancer cells to metabolic stress by disrupting actin cytoskeleton and inhibiting autophagic flux. Toxicol In Vitro. 2016 Dec;37:70-78.
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